Simplify Alpha has opened an AI engineering centre in Hyderabad’s HITEC City and plans to expand its workforce there to 1,000 professionals over the next two years, adding a significant new technology employment commitment to the city’s growing innovation economy.
The US-based healthcare technology company, part of Chicago-headquartered Simplify Group, said the centre will develop artificial intelligence solutions for operations in the US health insurance sector. Its teams will combine engineering capabilities with specialised knowledge of healthcare processes and insurance systems.
According to the company, the Hyderabad facility will follow its “domain forward deployed engineering” model. Under this approach, engineering teams work with healthcare organisations to identify operational bottlenecks and develop targeted AI-led solutions rather than deploying generic automation tools.
The centre’s work will cover the automation of manual processes and the integration of AI tools across claims, benefits, provider operations and member experience workflows. These functions involve interactions among health plans, healthcare providers and members, making domain knowledge an important part of the company’s engineering model.
Telangana IT and Industries Minister D Sridhar Babu, who inaugurated the facility, said the state had attracted more than 160 global innovation centres over the past two and a half years. He said the additions had reinforced Hyderabad’s position as a global hub for innovation and deep domain expertise.
Sridhar Babu said Simplify Alpha’s investment would create high-value jobs and strengthen local expertise, while enabling teams in Hyderabad to develop solutions for international markets. The company’s planned expansion would require the recruitment and training of professionals with both advanced technology skills and an understanding of US healthcare operations.
Simplify Alpha co-founder and chief executive Venkatgiri Vandali said Hyderabad’s technology talent and knowledge ecosystem would support the company’s next phase of growth as AI and agentic models reshape healthcare operations. He said the company already supports more than 70 major health plans.
The new centre is intended to serve as a strategic base for developing AI systems tailored to the complexities of the US health insurance market. The company said local engineers would be trained at the intersection of US healthcare ontology and advanced AI implementation, allowing them to take greater ownership of global health plan solutions.
The expansion adds to Simplify Alpha’s existing presence in India. The company already operates from Pune and Mumbai, while the Hyderabad centre will focus on building specialised engineering teams for its healthcare technology business.
The announcement also highlights how Hyderabad’s technology growth is increasingly linked to specialised, export-oriented work rather than only general software services. In this case, the proposed jobs are tied to an international healthcare workflow and require expertise in artificial intelligence, engineering and a regulated industry domain.
The company’s stated next step is to scale the Hyderabad workforce to 1,000 professionals over the next two years while developing AI solutions for health plans and their claims, benefits, provider and member operations.


